Aminoglycosides (e.g., tobramycin) or oral contraceptives (birth control pills) because their effectiveness may be decreased by Piperacillin/Tazobactam. Anticoagulants (e.g., warfarin) because their effectiveness may be decreased or the risk of their side effects may be decreased or the risk of their side effects may be increased by Piperacillin/Tazobactam chemotherapy or diuretics (e.g., furosemide, hydrochlorothiazide) because the risk of side effects, such as low blood potassium levels, may be increased. Heparin, methotrexate, or nondepolarizing muscle relaxants (e.g., vecuronium) because the risk of their side effects may be increased by Piperacillin/Tazobactam. Probenecid because may increase the risk of Piperacillin/Tazobactam's side effects Tetracyclines (e.g., doxycycline) because they may decrease Piperacillin/Tazobactam's effectiveness.
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